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Health and Longevity news (from KurzweilAI.net)

Scientists identify first genetic variant linked to biological aging in humans
Physorg.com, Feb. 7, 2010

The risk of age-associated diseases including heart disease and some types of cancers are more closely related to biological rather than chronological age,
European researchers have found, showing that telomere lengths depend on the presence of gene variants near a gene called TERC.


'Nanobubbles' kill cancer cells
Physorg.com, Feb. 4, 2010

Rice University have discovered a new technique for targeting individual diseased cells and destroying them with exploding "nanobubbles."

The nanobubbles are created when gold nanoparticles are struck by short laser pulses.


Researchers perform complete genomic sequencing of brain cancer cell line
Physorg.com, Jan. 29, 2010

Researchers at UCLA's Jonsson Comprehensive Cancer Center have performed the first complete genomic sequencing of a brain cancer cell line, a discovery that may lead to personalized treatments based on the unique biological signature of an individual's cancer and to more effective and less toxic drugs.
Firm Brings Gene Tests to Masses
New York Times, Jan. 28, 2010

Silicon Valley start-up Counsyl is selling a test that it says can tell couples whether they are at risk of having children for 100 inherited diseases, including rare inherited diseases.

Some genetic testing of prospective parents is done now, but only for a few diseases like cystic fibrosis and Tay-Sachs, and only for certain ethnic groups. Each test can cost hundreds or even thousands of dollars. Counsyl's test costs $349 for an individual or $698 for a couple.
Making Old Stem Cells Act Young Again
KurzweilAI.net, Jan. 28, 2010

In old mice, a several-week exposure to the blood of young mice causes their bone marrow stem cells to act "young" again, a team of Howard Hughes Medical Institute (HHMI) researchers has found, consistent with other recent studies that show stem-cell aging may be reversible.

Exposure to a younger animal's blood somehow pushed the older animal's hematopoietic stem cells (which give rise to all the cells of the blood system) back to a more youthful state, in which they were fewer in number but recovered nearly all of their blood-cell-generating capacity.




The Healthcare System: An Apple Tablet's Biggest Opportunity
ReadWriteWeb, Jan. 25, 2010

Apple's "iTablet" could be destined to transform our care delivery system in a major way.

The promise of improved clinical information systems, based on real-time information updates across patient touchpoints could be a workflow game changer. If the tablet becomes the tool that is carried with a nurse or doctor on their travels from patient to patient, it will save time, money and lives by enabling the first "always updated" system.
Towards Creating Blood Vessels
Technology Review, Jan. 26, 2010

researchers at Weill Cornell Medical College developed a simple way to increase production of endothelial cells -- which line the interior of blood vessels and give rise to blood vessels -- by more than 30-fold.

The cells might one day by used to create blood vessels in engineered tissue or administered to patients directly to repair injury after heart attack or stroke, resupplying blood to damaged organs.
Neuroscientists Say Brain Scans Can Spot PTSD
Wired Danger Room, Jan. 22, 2010

Researchers at the University of Minnesota and the Minneapolis VA Medical Center have found a distinct pattern of brain activity among PTSD sufferers, using a brain imaging method called magnetoencephalography (MEG).



Bacteria rewired to flash in sync
New Scientist Life, Jan. 20, 2009

University of California, San Diego researchers and colleagues have genetically engineered bacteria that fluoresce in synchronised bursts.

Controlling synchrony between cells might lead to implants made of engineered cells that act as a periodic drug delivery devices, or provide new insights into sleep, learning and brain diseases like Parkinson's and Alzheimer's, which are thought to occur when synchrony between neurons is abnormal.


Scientists identify molecule that inhibits stem cell differentiation
Physorg.com, Jan. 19, 2010

Scientists at the Stanford University School of Medicine have identified a molecule, DNMT1, that helps stem cells know whether to self-renew to create more stem cells, or to differentiate into specialized, non-dividing adult skin cells.

It's important because too much self-renewal can lead to cancer, and too little can inhibit wound healing.
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Health and Longevity articles (from KurzweilAI.net)

Bootstrapping our way to an ageless future
By Aubrey de Grey
(Added September 19th 2007)

Biomedical gerontologist Aubrey de Grey expects many people alive today to live to 1000 years of age and to avoid age-related health problems even at that age. In this excerpt from his just-published, much-awaited book, Ending Aging, he explains how.

Press ignores bias in study of multivitamins and prostate cancer
By Ray Kurzweil and Terry Grossman
(Added May 25th 2007)

In a recent paper reporting on the National Cancer Institute study of multivitamin use and the risk of prostate cancer, the NCI authors cited several possible bias factors. An analysis by Ray Kurzweil and Terry Grossman shows why the study’s biases should be considered before drawing conclusions.

Strategic Sustainable Brain
By Natasha Vita-More
(Added March 31st 2006)

The human brain faces a challenging future. To cope with accelerating nanotech- and biotech-based developments in an increasingly complex world, compete with emerging superintelligence, and maintain its performance and sustainability as people live longer, the fragile human brain will need major enhancements: a backup system, eliminating degenerative processes, direct mind-linkup to ubiquitous computing networks, error-correction for memory, and a global Net connection with remote neural access.

Nanoethics and Human Enhancement
By Patrick Lin and Fritz Allhoff
(Added March 31st 2006)

Radical nanotech-based human enhancements such as bionic implants and "respirocyte" artificial red blood cells will become technologically viable in the near future, raising profound ethical issues and forcing us to rethink what it means to be human. Recent pro-enhancement arguments will need to be critically examined and strengthened if they are to be convincing.

Reprogramming your Biochemistry for Immortality
By Ray Kurzweil
(Added March 8th 2006)

Scientists are now talking about people staying young and not aging. Ray Kurzweil is taking it a step further: "In addition to radical life extension, we’ll also have radical life expansion. The nanobots will be able to go inside the brain and extend our mental functioning by interacting with our biological neurons."

Nanotechnology, Nanomedicine and Nanosurgery
By Robert A. Freitas Jr.
(Added February 13th 2006)

The ability to build complex diamondoid medical nanorobots to molecular precision, and then to build them cheaply enough in sufficiently large numbers to be useful therapeutically, will revolutionize the practice of medicine and surgery.

Ray Kurzweil's Plan for Cheating Death
By Terry Grossman
(Added February 3rd 2006)

A cure for aging may be found in the next fifty years. The trick now is to live long enough to be there when it happens. In his two new books, Ray Kurzweil has painted a clear picture of the future and provided a blueprint for how to get there.

Interview with Robert A. Freitas Jr. Part 2
By Robert A. Freitas Jr. and Sander Olson
(Added February 2nd 2006)

There are very few diseases or conditions--including infectious diseases--aside from physical brain damage, that cannot be cured using nanomedicine, says nanomedicine pioneer Robert A. Freitas Jr. He believes nanomedicine's greatest power will emerge in a decade or two as we learn to design and construct complete artificial nanorobots using diamondoid nanometer-scale parts and subsystems.

Ray Kurzweil's Dangerous Idea
By Ray Kurzweil
(Added January 17th 2006)

"What is your dangerous idea?" Over one hundred big thinkers answered this question, as part of The Edge's Annual Question for 2006. Ray Kurzweil's dangerous idea? We can achieve immortality in our lifetime.

Open-Source Biology And Its Impact on Industry
By Rob Carlson
(Added March 3rd 2004)

Technology based on intentional, open-source biology is on its way, whether we like it or not. Distributed biological manufacturing is the future of the global economy and will occur as inexpensive, quality DNA sequencing and synthesis equipment becomes available to anyone. In 2050, garage biology hacking will be well under way. Fear of potential hazards should be met with increased research and education, rather than closing the door on the profound positive impacts that distributed biological technology will have on human health, human impacts on the environment, and increasing standards of living around the world.

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